Figure 1  .

The pedigree of the familial exudative vitreoretinopathy (FEVR) family described, segregating autosomal dominant FEVR, drawn using the program CYRILLIC 2. (A) A complete family tree, but many of the apparently normal individuals have not been examined by an ophthalmologist and the subtle nature of the FEVR phenotype in some cases is such that carrier status cannot be excluded. Solid symbols are confirmed as affected by clinical examination, those marked with a vertical line are said to be or to have been affected, those marked with a dot are asymptomatic obligate carriers, and those marked with a question mark have an uncertain diagnosis which is being investigated further. (B) A subset of (A) which has been subject to genetic analysis, and haplotypes for 11q markers are given below each symbol (reading downwards the haplotypes are obtained from markers D11S916, D11S527, D11S937, D11S1396, D11SS873, and D11S876). Affected individuals are also numbered (italic) to correspond with (A) and with Table 1.