Figure 1 .
Survival of T cell deficient mice. Mice were inoculated ocularly with 2×106 pfu of McKrae as described in Materials and method. Survival was measured 28 days after ocular challenge. (A) Survival of CD8−/− and CD8+ depleted mice compared with C57BL/6J control mice after ocular infection with HSV-1. CD8−/− mice (n=10), CD8+ depleted (n=9), and C57BL/6J (n=9). (B) Survival of CD4−/− and CD4+ depleted mice compared with C57BL/6J control mice after ocular infection with HSV-1. CD4−/− mice (n=14), CD4+ depleted (n=9), and C57BL/6J (n=10).