Figure 1  .

Localisation pattern of large transforming growth factor β binding protein-1 (LTBP-1) in human posterior capsule opacification. In (A) (case 1) and (B) (case 8), lens epithelium of an uninjured lens capsule (A, arrowheads) and a capsule 10 days after cataract surgery (B, arrowheads) lack LTBP-1. In (C) (case 17), extracellular matrix accumulation (asterisk) between the anterior lens capsule and the anterior surface of the intraocular lens shows immunoreactivity for LTBP-1. Lens cells are negative for this protein (arrowheads). In (D) (case 19), lens cells (arrowheads) and regenerated lenticular fibres of Sommerring's ring unstained for LTBP-1. AC = anterior capsule; IOL = intraocular lens. Indirect immunostaining; bar = 20 µm.