Figure 3  .

Fibrillin-1 as a component of fibrous extracellular matrix in human posterior capsule opacification. In (A) (case 2), uninjured lens epithelium (arrowheads) lacks immunoreactivity for fibrillin-1. In (B) (case 18), extracellular matrix accumulation (asterisk) around the edge of anterior capsulotomy (yellow arrow) shows marked immunoreactivity for fibrillin-1. In (C) (case 17), weak immunoreactivity for fibrillin-1 (arrows) is detected surrounding proliferating lens epithelial cells, which lack immunoreactivity. AC = anterior capsule; IOL = intraocular lens. Indirect immunostaining; bar = 20 µm.