Table 4.

Effect of protein intake on the distribution of lysine metabolism (μmol/kg per h) among the PDV, liver, and peripheral tissues

Diet	Whole-body metabolism			First-pass metabolism			Hepatic lysine oxidation
	Flux	Oxidation	NOLD	Total	Intestine	Liver
HP	799	77	722	119	−15	134	55
LP	712	18	694	143	91	53	18
PSEM	26	8	18	33	49	33	10
Diet effect	NS	P < 0.05	NS	NS	<0.05	<0.05	<0.01

	NOLD			Body protein degradation	Lysine balance
	PDV	Liver	Periphery		Body	PDV	Periphery + liver
HP	191	79	452	281	441	213	228
LP	217	35	492	505	189	186	3
PSEM	30	14	24	28	22	30	25
Diet effect	NS	=0.07	NS	<0.01	<0.001	NS	<0.001

NOLD, nonoxidative lysine disposal; PSEM, pooled standard error of the mean; NS, no statistically significant difference between pigs fed HP or LP diets.