Table 1.
Proteins containing Q/N-rich regions in S. cerevisiae fall into a broad spectrum of functional clusters
| Cluster | Protein | Q/N |
|---|---|---|
| Nonkinase signaling proteins | ||
| GPR1 | 55 | |
| RPI1 | 35 | |
| PHO81 | 34 | |
| Kinases | ||
| NPR1, ARP1 | 52 | |
| CBK1 | 49 | |
| YCK1 | 40 | |
| YCK2 | 36 | |
| HRR25 | 36 | |
| APG13 | 36 | |
| YAK1 | 33 | |
| SKY1 | 32 | |
| KSP1 | 32 | |
| SCH9 | 31 | |
| SKS1 | 31 | |
| YBR059 | 38 | |
| DNA/RNA binding | ||
| MPT5, HTR1 | 31 | |
| YPR042 | 51 | |
| YBR180 | 34 | |
| YGL014 | 34 | |
| YLL013 | 33 | |
| RNA processing | ||
| NAB1 | 48 | |
| LSM4 | 38 | |
| PCF11 | 37 | |
| NAB3 | 34 | |
| PUB1 | 33 | |
| RNA15 | 30 | |
| PSP2 | 33 | |
| NGR1 | 31 | |
| YBL051 | 30 | |
| Nucleoporins | ||
| NUP116 | 36 | |
| NUP100 | 32 | |
| NUP57 | 31 | |
| NUP49 | 30 | |
| Transcription | ||
| SNF5 | 66 | |
| CYC8 | 54 | |
| MCM1 | 49 | |
| IXR1, ORD1 | 49 | |
| MED2 | 48 | |
| GAL11 | 47 | |
| SWI11 | 43 | |
| TAF61 | 43 | |
| PDR1 | 38 | |
| URE2 | 38 | |
| DAL81 | 38 | |
| MOT3, HMS1 | 38 | |
| RLM1 | 36 | |
| SNF2, GAM1 | 36 | |
| SWI4 | 35 | |
| AZF1 | 35 | |
| CCR4 | 34 | |
| CRZ1 | 32 | |
| PDC2 | 32 | |
| DAT1 | 31 | |
| SFP1 | 30 | |
| SPT20 | 30 | |
| CDC39 | 30 | |
| YIL130 | 55 | |
| YEL007 | 46 | |
| YDR409 | 37 | |
| POP2 | 37 | |
| YMR263 | 35 | |
| EPL1 | 32 | |
| TBS1 | 31 | |
| YLR373 | 30 | |
| Translation | ||
| VAR1 | 40 | |
| SUP35 | 38 | |
| NEW1, YPL226 | 32 | |
| TIF4632 | 30 | |
| Vessicular trafficing/secretory pathway | ||
| ENT2 | 48 | |
| SEC61 | 45 | |
| YAP1801 | 39 | |
| PAN1 | 38 | |
| SLA2 | 38 | |
| ENT1 | 36 | |
| SCD5 | 36 | |
| FAB1 | 32 | |
| ANP1 | 31 | |
| YKL054 | 53 | |
| Outer membrane proteins | ||
| YDR213 | 44 | |
| YPR022 | 42 | |
| PSP1 | 31 | |
| YLR177 | 30 | |
| Other | ||
| RNQ1 | 42 | |
| CDC27 | 35 | |
| MAD1 | 34 | |
| GRR1 | 32 | |
| JSN1 | 31 | |
| SLF1 | 30 | |
| VAC7 | 30 | |
| YKR096 | 38 | |
| YGL066 | 37 | |
| YKL088 | 32 | |
| Unknown | ||
| MSS11 | 52 | |
| HOT1 | 33 | |
| YBR016 | 41 | |
| YBL081 | 38 | |
| YIL105 | 36 | |
| YBR238 | 33 | |
| YBL029 | 31 | |
| YOR197 | 30 | |
| YML053 | 30 | |
S. cerevisiae proteins containing Q/N-rich regions were placed into functional groups on the basis of either known biochemical function or sequence homology to proteins of known function (indicated by italics).