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Effect on paracellular transport of placing interferon γ (IFNγ) on the basal or apical side of HT29-19A intestinal cell monolayers for 48 or 72 hours. Paracellular permeability was measured as (A) ionic conductance (G), and (B) mannitol and (C) Na fluxes. *Significantly different from untreated cells (p⩽0.02); †significantly different from time matched cells after IFNγ treatment on the apical side (p⩽0.03). n = 8 to 20 filter grown intestinal monolayers.
