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Simplified diagram of mucosal glutathione synthesis in the ileum. GSH, glutathione; GSSG, glutathione disulphide; Gly, glycine; CysSH, cysteine; Cys-Cys, cystine; Glu, glutamate; AA, amino acid; γ-Glu-AA, γ-glutamyl-amino acid; γ-Glu-CysSH, γ-glutamylcysteine; Cys-Gly, cysteinylglycine. (1) Site of action of γ-glutamyl transferase; (2) site of action of γ-glutamylcysteine synthetase. For further information see introduction.
