Figure 5 .

Pro-oxidant glutathione status in the mucosa of freshly resected ileum in patients with Crohn's disease. Reduced glutathione (rGSH) is decreased in inflamed (n=26) as well as non-inflamed (n=21) mucosa in Crohn's disease. Oxidised glutathione (GSSG) is increased in areas of inflammation so that the redox status of glutathione, as defined by the ratio rGSH/GSSG, is heavily decreased in inflamed mucosa. Bars represent mean (SE). Statistical analysis was performed by the Student's t test including a Bonferroni's correction. **p<0.01, †p<10^-4 versus controls (n=21).