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Immunohistochemical staining for urokinase in terminal ileum and colon affected by inflammatory bowel disease. (A) Terminal ileum of a patient with Crohn's disease showing cytoplasmic staining of villous but not crypt epithelium (original magnification ×400). (B) Colonic mucosa of a patient with ulcerative colitis, showing distorted crypt architecture but heavy staining of surface epithelial cells and underlying basement membrane (original magnification ×400).
