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Correlation of (A) median crypt column height, (B) metaphase index, and (C) number of metaphase arrests per crypt column of distal colonic epithelium with median uPA activities (logarithm transformed) in homogenates of adjacent colonic mucosa in normal rats ingesting a variety of diets. Pearson correlation coefficients were −0.25 for crypt column height (p>0.1), 0.68 (p<0.005) for the number of arrests per crypt, and 0.75 (p<0.001) for the metaphase index.
