Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Acetylation of p53 at Lys-317 and -379 in wild-type and p53MND differentiated ES cells at 12 and 24 h after UV radiation. Differentiated ES cells were exposed to 60 J/M2 UV light and treated with 5 μM trichostatin A for 4 h before harvesting. Cell extracts from the irradiated and untreated controls were analyzed by Western blot with antibodies specific for p53 or p53 acetylated at Lys-317 or Lys-379. Acetylated p53 (Top and Middle) and total p53 (Bottom) are indicated with arrowheads.
