Figure 3 .

Expression of insulin-like growth factor-I receptor (IGF-IR) mRNA in adenocarcinoma of the colon (CRC) compared with that in tissue adjacent to the carcinoma (Adj-CRC). mRNA levels were measured by solution hybridisation RNase protection assay as described in Methods. The values are the relative density of the bands as percentage of the normal adjacent tissue consisting of 12 specimens from six individuals and 12 specimens of tissue from the adenocarcinoma obtained from the same six individuals. Results are mean (SEM). There was a highly significant difference (*p<0.0001) between the two groups.