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Differential effects of all-trans-retinoic acid on transactivation. HT29 and LoVo cells were transiently transfected with the pTK::βREx2-luc reporter construct. After incubation with the indicated concentrations of all-trans RA for 24 hours, luciferase activity was determined and expressed as fold increase over basal (luciferase activity in the absence of retinoids). Values are mean (SEM) from six independent experiments, each performed in triplicate wells.
