Figure 2  .

Structure of the mucosal adhesion antigens. The mosaic nature of L-selectin, mucosal addressin cell adhesion molecule (MAdCAM) 1 and special carbohydrate containing forms of MAdCAM-1 (MAdCAM-1 CHO) is shown together with the prototypic structure of integrins and intercellular adhesion molecules (ICAM). Lectin, C-type (calcium dependent) lectin domain; EGF-like, epidermal growth factor-like domain; and CR, complement regulatory protein-like motif in selectins. Metal binding = divalent cation binding repeats in α subunits of integrins; I-domain = inserted domain in αL subunit of lymphocyte function associated antigen (LFA) 1 and I-domain-like, a putative inserted domain-like area in β subunits of integrins.