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Inhibition of cAMP potentiated NO2 production by the tyrosine kinase inhibitor, tyrphostin A25 (A) and the JAK-2 inhibitor, tyrphostin B42 (B) in DLD-1 cells. Cells were treated in serum free medium for 24 hours with cytomix and 8Br-cAMP or Db-cAMP. Results are expressed as percentage of maximal induction (without tyrphostin) and represent means (SEM) from at least three different experiments, each done in triplicate.
