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Immunohistochemical staining of hMSH2 and hMLH1 using consecutive tissue sections (original magnification × 160). (A) Positive staining of normal control mucosa (N) and adjacent carcinoma (C) with hMSH2. (B) Positive staining of normal control mucosa (N); loss of hMLH1 protein expression in the adjacent carcinoma (C) is clearly evident. Intervening stromal cells are positive.
