Figure 5  .

Localisation of KC immunostaining in inflamed rat mesenteric postcapillary venules. Typical micrographs of the ileal section of rat mesentery whole mounts. (A) Preparations excised two hours after administration of 20 ng rat interleukin (IL) 1β and incubated with non-specific rabbit IgG. Arrowheads indicate some of the perivenular mast cells. (B) As in A, but the tissue was incubated with specific rabbit antirat KC IgG. Arrowheads indicate some of the perivenular mast cells which stained for KC. (C) As in B, but the rat was treated with 100 µg/kg subcutaneous dexamethasone one hour prior to intraperitoneal injection of IL-1β. Arrowheads indicate some of the perivenular mast cells which appeared less stained for KC when compared with B. Pictures are representative of four distinct preparations. L, vessel lumen. Bar, 25 µm.