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Figure 1  .

Figure 1  

Sample of four loci showing bandshifts, including three microsatellite loci (D2S123, BAT40, and c-myb) and the poly(A)8 tract of hMSH3. DNA was extracted from a 2 mm tubular adenoma from a patient carrying a germline mutation of hMSH2. Despite the small size of the adenoma, all nine microsatellite loci showed instability, as did hMSH6 (not shown). N, normal; T, tumour DNA.