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Quantitative estimation of lacZ expression in the liver by intravenous administration of adenoviruses. Mice with normal, cirrhotic, and fulminant hepatitis livers were infused intravenously with adenoviruses (2×108 pfu/200 µl) carrying the lacZ gene. Animals were killed on day 4 after adenoviral infusion and lacZ gene expression was quantitatively estimated using the chemiluminescent reporter gene assay system. Each group consisted of eight animals. *0.01<p<0.05, ***p<0.001.
