Figure 1  .

(A) Enteroendocrine cell counts per 100 epithelial cells in the patient cohort at visits 1, 2, and 3 compared with controls and post-dysenteric irritable bowel syndrome (PD-IBS) patients. ***Significantly increased compared with controls, p<0.001. Values at visits 2 and 3 were significantly lower than those at visit 1, p<0.05. (B) Rectal biopsy stained for synaptophysin showing increased numbers of enteroendocrine cells in the colonic crypt base of a patient three weeks after infection with Campylobacter jejuni. A control biopsy is shown (C) for comparison. Original magnification: ×40. Synaptophysin positive cells are brown, with blue haematoxylin counterstain. CD3, CD4, and CD8 lamina propria lymphocyte counts (table 5)