Figure 1  .

Thioacetamide (TAA) induced small intestinal injury. (A) Twenty four hours after administration of TAA (40 mg/kg) to mice, the normal villus structure of the jejunum and ileum is lost and marked necrosis is seen within the remaining mucosa. (B) Administration of epidermal growth factor (EGF, 30 µg/kg), 30 minutes prior to TAA, markedly preserved small intestinal architecture. Similar preservation was seen when a dose of 10 µg/kg of EGF was used (not shown). Tissues were stained with haematoxylin and eosin. Original magnification ×10. Bar=100 µm.