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Normal terminal ileal mucosa (A) stained with anti-human defensin 5 (HD-5) antiserum showing occasional villous epithelial cells strongly immunoreactive for HD-5. (B) Section from the same specimen as (A) and stained with anti-HD-5 antiserum that had been preadsorbed with synthetic HD-5. Positive staining of HD-5 containing Paneth cells and villous epithelial cells is completely abolished.
