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Figure 9  .

Figure 9  

Effect of calpain inhibitor I (CALP-1) on neutrophil infiltration and lipid peroxidation. Myeloperoxidase (MPO) activity (A) and malondialdehyde (MDA) levels (B) in the colon from dinitrobenzene sulphonic acid (DNBS) treated rats. MPO activity and MDA levels were significantly increased in DNBS treated rats in comparison with sham controls. CALP-1 treated rats showed a significant reduction in MPO activity and MDA levels. Values are mean (SEM) of 10 rats in each group. **p<0.01 v sham; ††p<0.01 v DNBS.