Figure 1  .

Effect of chronic stress on colonic physiology and macromolecule permeability. Mast cell deficient rats (Ws/Ws) and their normal mast cell containing littermates (+/+) were submitted to sham stress or water avoidance stress for five consecutive days. (A) Baseline short circuit current (Isc), (B) conductance (G), and (C) horseradish peroxidase (HRP) flux studied in Ussing chambers six hours after the final sham/stress session. Bars represent mean (SEM); n=6 rats/group, with 2-4 tissues averaged per rat. **p<0.01 v all other groups.