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Phosphorylation of ERK1/2 by Helicobacter pylori (HP). Immunoblot analysis showing phospho-ERK1/2 (top panel) and total ERK1/2 (bottom panel) in TMK1 cells cocultured with H pylori. Antibodies used react with both ERK1 and ERK2. Stimulation by epidermal growth factor (EGF 10 ng/ml for 60 minutes) was used as a positive control.
