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Absolute (non-infused arm, squares; infused arm, triangles) and percentage change in forearm blood flow responses (circles), with intermittent application (arrows) of lower body negative pressure (LBNP), to saline and losartan (30 and 90 µg/min) infusion in healthy control subjects (empty symbols) and patients with heart failure (filled symbols). *p < 0.001 (one way ANOVA, v baseline saline infusion); †p = 0.008 (two way ANOVA, basal v LBNP).
