Figure 1 Restriction fragment length patterns of representative human papillomavirus (HPV) genotypes obtained by endonuclease digestion of L1 open reading frame (ORF) PCR products. Lane M: 25 bp ladder marker. Lanes 1–3: HPV6 not restricted, restricted with RsaI, and restricted with DdeI, respectively. Lane 4: blank. Lanes 5–7: HPV11 not restricted, restricted with RsaI, and restricted with DdeI, respectively. Lane 8: blank. Lanes 9–11: HPV33 not restricted, restricted with RsaI, and restricted with DdeI, respectively. Lanes 12–14: HPV58 not restricted, restricted with RsaI, and restricted with DdeI, respectively. Lane 15: blank. Lanes 16–18: HPV16 not restricted, restricted with RsaI, and restricted with DdeI, respectively. Lane 19: blank. Lanes 20–22: HPV18 not restricted, restricted with RsaI, and restricted with DdeI, respectively.