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. 2000 Oct 17;97(22):12210–12215. doi: 10.1073/pnas.210391497

Figure 4.

Figure 4

Cytotoxicity of CD8+ T cell lines against MTB-infected macrophages. Macrophages from a heterologous HLA-A*0201 donor were infected with MTB at a multiplicity of infection of 5–10 bacilli per cell (a and b), or THP-1 were infected at a multiplicity of infection of 5–10 bacilli per cell (c). MTB-infected and corresponding peptide-pulsed THP-1 cells were tested for lysis by 51Cr release assay by incubation with (a) ThyA30–38 peptide-specific line (M23–091), (b) PstA175–83 peptide-specific line, and (c) 85B15–23 peptide-specific line (N11–023).