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Inhibition of the growth of intracellular MTB by peptide-specific CD8+ T cells. MTB peptide-specific CD8+ T cell lines were coincubated with MTB-infected THP-1 cells in the presence or absence of MTB-derived peptides or a control peptide at an effector-to-target ratio of 20:1. Cells were lysed and CFU determined. The CFU of infected THP-1 without T cells at 24 h was 167,000 for the experiment in which M23–091 was tested and 66,400 for the experiment in which M22.029 was tested.
