Figure 4.

Normal circadian activity, motor functions, and long-term potentiation (LTP) in rgs2^−/− mice. (A) Circadian activity was monitored during a 24-h period (12-h light/dark cycles). Mean crosses accumulated per 30-min intervals ± SD are shown. (B) Normal motor function in a rotarod test. Mean values of retention times (latency) ± SD are shown. Trials indicate a stepwise increase in rotarod speed (10–40 rpm, 5-rpm increase per trial). (C) Tetanus-induced LTP in CA1 neurons. Averaged normalized field EPSP (fEPSP) slope measurements obtained from 11 hippocampus slices of 4 rgs2^+/− and 4 rgs2^−/− mice.