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Impaired basal electric activity in CA1 neurons of rgs2−/− mice. (A and B) Reduction of input/output relationship in CA1 pathway in rgs2−/− mice. Superimposed recordings of CA1 field excitatory postsynaptic potentials (fEPSP) evoked by electrical stimulation of Schaffer collateral input. Input: peak amplitude of presynaptic volley. Output: field EPSP slope measured at 10–65% rising phase of EPSP. Data are from seven hippocampus slices of four rgs2+/− and four rgs2−/− mice.
