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. 2000 Oct 24;97(22):12312–12317. doi: 10.1073/pnas.97.22.12312

Figure 5.

Figure 5

Basal properties of MPP-dentate granule cell synapses are altered in GFRα2 −/− mice. The initial slope of the field excitatory postsynaptic potential plotted against the presynaptic fiber volley for Schaffer collateral-CA1 (A) and LPP- and MPP-dentate granule cell synapses (B and C, respectively). Note the significantly lower efficacy of excitatory transmission in MPP-granule cell synapses in GFRα2 −/− mice. No differences are observed between wild-type and knock-out animals for Schaffer collateral-CA1 and LPP-granule cell synapses. Paired-pulse facilitation in Schaffer collateral-CA1 (D) and LPP-granule cell synapses (E), and PPD in MPP-dentate granule cell synapses (F), respectively, are not altered in GFRα2 −/− mice. *, P < 0.05, Student's unpaired t test. Data are obtained from four to six slices of GFRα2 +/+ and −/− mice, respectively.