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Fat pad measurements. Adipose tissue from four fat depots (retroperitoneal, inguinal, reproductive, and scapular) were dissected and weighed. (A) Fat pad measurements from 12 WT, 14 PF Mc4r-null, and 10 NPF Mc4r-null female mice. (B) Fat pad measurements from14 WT, eight PF Mc4r-null, and 13 NPF Mc4r-null male mice. *, Significant difference from WT mice (P < 0.001). #, Significant difference between NPF Mc4r-null and PF mice (P < 0.001).
