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. 1995 Aug;63(8):3235–3238. doi: 10.1128/iai.63.8.3235-3238.1995

S fimbriae of uropathogenic Escherichia coli bind to primary human renal proximal tubular epithelial cells but do not induce expression of intercellular adhesion molecule 1.

B Kreft 1, M Placzek 1, C Doehn 1, J Hacker 1, G Schmidt 1, G Wasenauer 1, M R Daha 1, F J van der Woude 1, K Sack 1
PMCID: PMC173445  PMID: 7622256

Abstract

We have recently reported an increase of expression of the intercellular adhesion molecule 1 by renal carcinoma cells in response to S fimbriae of Escherichia coli. Now we demonstrate that E. coli expressing S and P fimbriae strongly binds to human proximal tubular epithelial cells. However, in primary and simian virus 40-transfected renal tubular epithelial cells S fimbriae do not enhance the expression of intercellular adhesion molecule 1.

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Selected References

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