. Author manuscript; available in PMC: 2007 Jan 9.

Published in final edited form as: Cancer Lett. 2006 Feb 14;245(1-2):163–170. doi: 10.1016/j.canlet.2006.01.003

Table 3.

The genetic profile of the TGF-β/activin-Smad pathways in the 8 HNSCC cell lines

Cell lines	ACVRIB	TGFBRI	TGFBRII	SMAD2	SMAD3	SMAD4
RPMI 2650	-	-	-	-	-	-
A253	-	-	missense¹	-	-	-
SW 579	-	-	-	-	-	-
Detroit 562	-	-	-	-	-	-
FaDu	-	-	-	-	-	HD¹
CAL27	-	-	-	-	-	nonsense²
SCC-15	-	-	-	missense²	-	-
SCC-25	-	-	-	-	-	-

-, absence of biallelic inactivation; HD, homozygous deletion; missense, missense mutation with presumed LOH; nonsense, nonsense mutation with presumed LOH.

as previously reported and confirmed in this study [8, 16].

mutations uncovered in the present study.