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- Adcock I. M., Shirasaki H., Gelder C. M., Peters M. J., Brown C. R., Barnes P. J. The effects of glucocorticoids on phorbol ester and cytokine stimulated transcription factor activation in human lung. Life Sci. 1994;55(14):1147–1153. doi: 10.1016/0024-3205(94)00243-6. [DOI] [PubMed] [Google Scholar]
- Arnaud A., Charpin J. Interaction between corticosteroids and beta 2-agonists in acute asthma. Eur J Respir Dis Suppl. 1982;122:126–131. [PubMed] [Google Scholar]
- Aziz I., McFarlane L. C., Lipworth B. J. Concomitant inhaled corticosteroid resensitises cardiac beta2-adrenoceptors in the presence of long-acting beta2-agonist therapy. Eur J Clin Pharmacol. 1998 Jul;54(5):377–381. doi: 10.1007/s002280050478. [DOI] [PubMed] [Google Scholar]
- Baraniuk J., Murray J. J., Nathan R. A., Berger W. E., Johnson M., Edwards L. D., Srebro S., Rickard K. A. Fluticasone alone or in combination with salmeterol vs triamcinolone in asthma. Chest. 1999 Sep;116(3):625–632. doi: 10.1378/chest.116.3.625. [DOI] [PubMed] [Google Scholar]
- Barnes P. J. Beta-adrenergic receptors and their regulation. Am J Respir Crit Care Med. 1995 Sep;152(3):838–860. doi: 10.1164/ajrccm.152.3.7663795. [DOI] [PubMed] [Google Scholar]
- Barnes P. J., O'Connor B. J. Use of a fixed combination beta 2-agonist and steroid dry powder inhaler in asthma. Am J Respir Crit Care Med. 1995 Apr;151(4):1053–1057. doi: 10.1164/ajrccm.151.4.7697230. [DOI] [PubMed] [Google Scholar]
- Bennati D., Piacentini G. L., Peroni D. G., Sette L., Testi R., Boner A. L. Changes in bronchial reactivity in asthmatic children after treatment with beclomethasone alone or in association with salbutamol. J Asthma. 1989;26(6):359–364. doi: 10.3109/02770908909073279. [DOI] [PubMed] [Google Scholar]
- Booth H., Bish R., Walters J., Whitehead F., Walters E. H. Salmeterol tachyphylaxis in steroid treated asthmatic subjects. Thorax. 1996 Nov;51(11):1100–1104. doi: 10.1136/thx.51.11.1100. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cockcroft D. W., Swystun V. A., Bhagat R. Interaction of inhaled beta 2 agonist and inhaled corticosteroid on airway responsiveness to allergen and methacholine. Am J Respir Crit Care Med. 1995 Nov;152(5 Pt 1):1485–1489. doi: 10.1164/ajrccm.152.5.7582281. [DOI] [PubMed] [Google Scholar]
- Crane J., Pearce N., Flatt A., Burgess C., Jackson R., Kwong T., Ball M., Beasley R. Prescribed fenoterol and death from asthma in New Zealand, 1981-83: case-control study. Lancet. 1989 Apr 29;1(8644):917–922. doi: 10.1016/s0140-6736(89)92505-1. [DOI] [PubMed] [Google Scholar]
- Dahl R., Pedersen B., Hägglöf B. Nocturnal asthma: effect of treatment with oral sustained-release terbutaline, inhaled budesonide, and the two in combination. J Allergy Clin Immunol. 1989 Apr;83(4):811–815. doi: 10.1016/0091-6749(89)90019-5. [DOI] [PubMed] [Google Scholar]
- Dalmasso F., Prota R. Snoring: analysis, measurement, clinical implications and applications. Eur Respir J. 1996 Jan;9(1):146–159. doi: 10.1183/09031936.96.09010146. [DOI] [PubMed] [Google Scholar]
- Davies A. O., De Lean A., Lefkowitz R. J. Myocardial beta-adrenergic receptors from adrenalectomized rats: impaired formation of high-affinity agonist-receptor complexes. Endocrinology. 1981 Feb;108(2):720–722. doi: 10.1210/endo-108-2-720. [DOI] [PubMed] [Google Scholar]
- Davies A. O., Lefkowitz R. J. Regulation of beta-adrenergic receptors by steroid hormones. Annu Rev Physiol. 1984;46:119–130. doi: 10.1146/annurev.ph.46.030184.001003. [DOI] [PubMed] [Google Scholar]
- Dompeling E., van Schayck C. P., van Grunsven P. M., van Herwaarden C. L., Akkermans R., Molema J., Folgering H., van Weel C. Slowing the deterioration of asthma and chronic obstructive pulmonary disease observed during bronchodilator therapy by adding inhaled corticosteroids. A 4-year prospective study. Ann Intern Med. 1993 May 15;118(10):770–778. doi: 10.7326/0003-4819-118-10-199305150-00003. [DOI] [PubMed] [Google Scholar]
- Dong Y., Aronsson M., Gustafsson J. A., Okret S. The mechanism of cAMP-induced glucocorticoid receptor expression. Correlation to cellular glucocorticoid response. J Biol Chem. 1989 Aug 15;264(23):13679–13683. [PubMed] [Google Scholar]
- Eickelberg O., Roth M., Lörx R., Bruce V., Rüdiger J., Johnson M., Block L. H. Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J Biol Chem. 1999 Jan 8;274(2):1005–1010. doi: 10.1074/jbc.274.2.1005. [DOI] [PubMed] [Google Scholar]
- Ellul-Micallef R., Fenech F. F. Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness. Lancet. 1975 Dec 27;2(7948):1269–1271. doi: 10.1016/s0140-6736(75)90608-x. [DOI] [PubMed] [Google Scholar]
- Emorine L. J., Marullo S., Delavier-Klutchko C., Kaveri S. V., Durieu-Trautmann O., Strosberg A. D. Structure of the gene for human beta 2-adrenergic receptor: expression and promoter characterization. Proc Natl Acad Sci U S A. 1987 Oct;84(20):6995–6999. doi: 10.1073/pnas.84.20.6995. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gauvreau G. M., Jordana M., Watson R. M., Cockroft D. W., O'Byrne P. M. Effect of regular inhaled albuterol on allergen-induced late responses and sputum eosinophils in asthmatic subjects. Am J Respir Crit Care Med. 1997 Dec;156(6):1738–1745. doi: 10.1164/ajrccm.156.6.96-08042. [DOI] [PubMed] [Google Scholar]
- Geddes B. A., Jones T. R., Dvorsky R. J., Lefcoe N. M. Interaction of glucocorticoids and bronchodilators on isolated guinea pig tracheal and human bronchial smooth muscle. Am Rev Respir Dis. 1974 Oct;110(4):420–427. doi: 10.1164/arrd.1974.110.4.420. [DOI] [PubMed] [Google Scholar]
- Giannini D., Bacci E., Dente F. L., Di Franco A., Vagaggini B., Testi R., Paggiaro P. Inhaled beclomethasone dipropionate reverts tolerance to the protective effect of salmeterol on allergen challenge. Chest. 1999 Mar;115(3):629–634. doi: 10.1378/chest.115.3.629. [DOI] [PubMed] [Google Scholar]
- Grainger J., Woodman K., Pearce N., Crane J., Burgess C., Keane A., Beasley R. Prescribed fenoterol and death from asthma in New Zealand, 1981-7: a further case-control study. Thorax. 1991 Feb;46(2):105–111. doi: 10.1136/thx.46.2.105. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greening A. P., Ind P. W., Northfield M., Shaw G. Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Allen & Hanburys Limited UK Study Group. Lancet. 1994 Jul 23;344(8917):219–224. doi: 10.1016/s0140-6736(94)92996-3. [DOI] [PubMed] [Google Scholar]
- Grove A., Lipworth B. J. Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients. Lancet. 1995 Jul 22;346(8969):201–206. doi: 10.1016/s0140-6736(95)91265-7. [DOI] [PubMed] [Google Scholar]
- Guideri G., Barletta M. A., Lehr D. Extraordinary potentiation of isoproterenol cardiotoxicity by corticoid pretreatment. Cardiovasc Res. 1974 Nov;8(6):775–786. doi: 10.1093/cvr/8.6.775. [DOI] [PubMed] [Google Scholar]
- Haahtela T., Alanko K., Muittari A., Lahdensuo A., Sahlström K., Vilkka V. The superiority of combination beclomethasone and salbutamol over standard dosing of salbutamol in the treatment of chronic asthma. Ann Allergy. 1989 Jan;62(1):63–66. [PubMed] [Google Scholar]
- Hadcock J. R., Malbon C. C. Regulation of beta-adrenergic receptors by "permissive" hormones: glucocorticoids increase steady-state levels of receptor mRNA. Proc Natl Acad Sci U S A. 1988 Nov;85(22):8415–8419. doi: 10.1073/pnas.85.22.8415. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hancox R. J., Aldridge R. E., Cowan J. O., Flannery E. M., Herbison G. P., McLachlan C. R., Town G. I., Taylor D. R. Tolerance to beta-agonists during acute bronchoconstriction. Eur Respir J. 1999 Aug;14(2):283–287. doi: 10.1034/j.1399-3003.1999.14b08.x. [DOI] [PubMed] [Google Scholar]
- Hancox R. J., Cowan J. O., Flannery E. M., Herbison G. P., McLachlan C. R., Wong C. S., Taylor D. R. Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma. Thorax. 1999 Jun;54(6):482–487. doi: 10.1136/thx.54.6.482. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hancox R. J., Stevens D. A., Adcock I. M., Barnes P. J., Taylor D. R. Effects of inhaled beta agonist and corticosteroid treatment on nuclear transcription factors in bronchial mucosa in asthma. Thorax. 1999 Jun;54(6):488–492. doi: 10.1136/thx.54.6.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hausdorff W. P., Caron M. G., Lefkowitz R. J. Turning off the signal: desensitization of beta-adrenergic receptor function. FASEB J. 1990 Aug;4(11):2881–2889. [PubMed] [Google Scholar]
- Hjemdahl P., Zetterlund A., Larsson K. Beta 2-agonist treatment reduces beta 2-sensitivity in alveolar macrophages despite corticosteroid treatment. Am J Respir Crit Care Med. 1996 Feb;153(2):576–581. doi: 10.1164/ajrccm.153.2.8564101. [DOI] [PubMed] [Google Scholar]
- Horn C. R., Clark T. J., Cochrane G. M. Can the morbidity of asthma be reduced by high dose inhaled therapy? A prospective study. Respir Med. 1990 Jan;84(1):61–66. doi: 10.1016/s0954-6111(08)80096-0. [DOI] [PubMed] [Google Scholar]
- Hui K. K., Conolly M. E., Tashkin D. P. Reversal of human lymphocyte beta-adrenoceptor desensitization by glucocorticoids. Clin Pharmacol Ther. 1982 Nov;32(5):566–571. doi: 10.1038/clpt.1982.204. [DOI] [PubMed] [Google Scholar]
- Janknecht R., Hunter T. Transcription. A growing coactivator network. Nature. 1996 Sep 5;383(6595):22–23. doi: 10.1038/383022a0. [DOI] [PubMed] [Google Scholar]
- Jones S. L., Taylor D. R. Excessive use of inhaled salbutamol: the potential benefits of dose-reduction. A case report. N Z Med J. 1999 Nov 26;112(1100):448–450. [PubMed] [Google Scholar]
- Kalra S., Swystun V. A., Bhagat R., Cockcroft D. W. Inhaled corticosteroids do not prevent the development of tolerance to the bronchoprotective effect of salmeterol. Chest. 1996 Apr;109(4):953–956. doi: 10.1378/chest.109.4.953. [DOI] [PubMed] [Google Scholar]
- Kerstjens H. A., Brand P. L., Hughes M. D., Robinson N. J., Postma D. S., Sluiter H. J., Bleecker E. R., Dekhuijzen P. N., de Jong P. M., Mengelers H. J. A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease. Dutch Chronic Non-Specific Lung Disease Study Group. N Engl J Med. 1992 Nov 12;327(20):1413–1419. doi: 10.1056/NEJM199211123272003. [DOI] [PubMed] [Google Scholar]
- Kobilka B. K., Dixon R. A., Frielle T., Dohlman H. G., Bolanowski M. A., Sigal I. S., Yang-Feng T. L., Francke U., Caron M. G., Lefkowitz R. J. cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proc Natl Acad Sci U S A. 1987 Jan;84(1):46–50. doi: 10.1073/pnas.84.1.46. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Korn S. H., Wouters E. F., Wesseling G., Arends J. W., Thunnissen F. B. Interaction between glucocorticoids and beta2-agonists: alpha and beta glucocorticoid-receptor mRNA expression in human bronchial epithelial cells. Biochem Pharmacol. 1998 Dec 15;56(12):1561–1569. doi: 10.1016/s0006-2952(98)00179-8. [DOI] [PubMed] [Google Scholar]
- Leblanc P., Knight A., Kreisman H., Borkhoff C. M., Johnston P. R. A placebo-controlled, crossover comparison of salmeterol and salbutamol in patients with asthma. Am J Respir Crit Care Med. 1996 Aug;154(2 Pt 1):324–328. doi: 10.1164/ajrccm.154.2.8756801. [DOI] [PubMed] [Google Scholar]
- Lin R. Y., Newman T. G., Sauter D., Sirleaf J., Walters J., Fox S., Tavakol M. Association between reported use of inhaled triamcinolone and differential short-term responses to aerosolized albuterol in asthmatics in an emergency department setting. Chest. 1994 Aug;106(2):452–457. doi: 10.1378/chest.106.2.452. [DOI] [PubMed] [Google Scholar]
- Mak J. C., Nishikawa M., Shirasaki H., Miyayasu K., Barnes P. J. Protective effects of a glucocorticoid on downregulation of pulmonary beta 2-adrenergic receptors in vivo. J Clin Invest. 1995 Jul;96(1):99–106. doi: 10.1172/JCI118084. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Malbon C. C., Hadcock J. R. Evidence that glucocorticoid response elements in the 5'-noncoding region of the hamster beta 2-adrenergic receptor gene are obligate for glucocorticoid regulation of receptor mRNA levels. Biochem Biophys Res Commun. 1988 Jul 29;154(2):676–681. doi: 10.1016/0006-291x(88)90192-1. [DOI] [PubMed] [Google Scholar]
- Manolitsas N. D., Wang J., Devalia J. L., Trigg C. J., McAulay A. E., Davies R. J. Regular albuterol, nedocromil sodium, and bronchial inflammation in asthma. Am J Respir Crit Care Med. 1995 Jun;151(6):1925–1930. doi: 10.1164/ajrccm.151.6.7767541. [DOI] [PubMed] [Google Scholar]
- McDevitt D. G., Shanks R. G., Swanton J. G. Further observations on the cardiotoxicity of isoprenaline during hypoxia. Br J Pharmacol. 1974 Mar;50(3):335–344. doi: 10.1111/j.1476-5381.1974.tb09608.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McGraw D. W., Liggett S. B. Heterogeneity in beta-adrenergic receptor kinase expression in the lung accounts for cell-specific desensitization of the beta2-adrenergic receptor. J Biol Chem. 1997 Mar 14;272(11):7338–7344. doi: 10.1074/jbc.272.11.7338. [DOI] [PubMed] [Google Scholar]
- Molema J., Lammers J. W., van Herwaarden C. L., Folgering H. T. Effects of inhaled beclomethasone dipropionate on beta 2-receptor function in the airways and adrenal responsiveness in bronchial asthma. Eur J Clin Pharmacol. 1988;34(6):577–583. doi: 10.1007/BF00615220. [DOI] [PubMed] [Google Scholar]
- Molfino N. A., Nannini L. J., Martelli A. N., Slutsky A. S. Respiratory arrest in near-fatal asthma. N Engl J Med. 1991 Jan 31;324(5):285–288. doi: 10.1056/NEJM199101313240502. [DOI] [PubMed] [Google Scholar]
- Murray J. J., Church N. L., Anderson W. H., Bernstein D. I., Wenzel S. E., Emmett A., Rickard K. A. Concurrent use of salmeterol with inhaled corticosteroids is more effective than inhaled corticosteroid dose increases. Allergy Asthma Proc. 1999 May-Jun;20(3):173–180. doi: 10.2500/108854199778553028. [DOI] [PubMed] [Google Scholar]
- Newnham D. M., Grove A., McDevitt D. G., Lipworth B. J. Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients. Thorax. 1995 May;50(5):497–504. doi: 10.1136/thx.50.5.497. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nielson C. P., Hadjokas N. E. Beta-adrenoceptor agonists block corticosteroid inhibition in eosinophils. Am J Respir Crit Care Med. 1998 Jan;157(1):184–191. doi: 10.1164/ajrccm.157.1.9704070. [DOI] [PubMed] [Google Scholar]
- Oddera S., Silvestri M., Testi R., Rossi G. A. Salmeterol enhances the inhibitory activity of dexamethasone on allergen-induced blood mononuclear cell activation. Respiration. 1998;65(3):199–204. doi: 10.1159/000029260. [DOI] [PubMed] [Google Scholar]
- Pansegrouw D. F., Weich D. J., le Roux F. P. Beta-adrenergic receptor tachyphylaxis in acute severe asthma. A preliminary communication. S Afr Med J. 1991 Sep 7;80(5):229–230. [PubMed] [Google Scholar]
- Pauwels R. A., Löfdahl C. G., Postma D. S., Tattersfield A. E., O'Byrne P., Barnes P. J., Ullman A. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med. 1997 Nov 13;337(20):1405–1411. doi: 10.1056/NEJM199711133372001. [DOI] [PubMed] [Google Scholar]
- Pearce N., Crane J., Burgess C., Jackson R., Beasley R. Beta agonists and asthma mortality: déjà vu. Clin Exp Allergy. 1991 Jul;21(4):401–410. doi: 10.1111/j.1365-2222.1991.tb01679.x. [DOI] [PubMed] [Google Scholar]
- Pearce N., Grainger J., Atkinson M., Crane J., Burgess C., Culling C., Windom H., Beasley R. Case-control study of prescribed fenoterol and death from asthma in New Zealand, 1977-81. Thorax. 1990 Mar;45(3):170–175. doi: 10.1136/thx.45.3.170. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pearlman D. S., Stricker W., Weinstein S., Gross G., Chervinsky P., Woodring A., Prillaman B., Shah T. Inhaled salmeterol and fluticasone: a study comparing monotherapy and combination therapy in asthma. Ann Allergy Asthma Immunol. 1999 Mar;82(3):257–265. doi: 10.1016/S1081-1206(10)62606-3. [DOI] [PubMed] [Google Scholar]
- Peters M. J., Adcock I. M., Brown C. R., Barnes P. J. Beta-adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung. Eur J Pharmacol. 1995 Apr 28;289(2):275–281. doi: 10.1016/0922-4106(95)90104-3. [DOI] [PubMed] [Google Scholar]
- Reisman R. E. Asthma induced by adrenergic aerosols. J Allergy. 1970 Sep;46(3):162–177. doi: 10.1016/0021-8707(70)90095-x. [DOI] [PubMed] [Google Scholar]
- Rodrigo G., Rodrigo C. Inhaled flunisolide for acute severe asthma. Am J Respir Crit Care Med. 1998 Mar;157(3 Pt 1):698–703. doi: 10.1164/ajrccm.157.3.9704022. [DOI] [PubMed] [Google Scholar]
- Russell G., Williams D. A., Weller P., Price J. F. Salmeterol xinafoate in children on high dose inhaled steroids. Ann Allergy Asthma Immunol. 1995 Nov;75(5):423–428. [PubMed] [Google Scholar]
- Scarcériaux V., Pélaprat D., Forgez P., Lhiaubet A. M., Rostène W. Effects of dexamethasone and forskolin on neurotensin production in rat hypothalamic cultures. Endocrinology. 1995 Jun;136(6):2554–2560. doi: 10.1210/endo.136.6.7750477. [DOI] [PubMed] [Google Scholar]
- Sears M. R., Taylor D. R., Print C. G., Lake D. C., Li Q. Q., Flannery E. M., Yates D. M., Lucas M. K., Herbison G. P. Regular inhaled beta-agonist treatment in bronchial asthma. Lancet. 1990 Dec 8;336(8728):1391–1396. doi: 10.1016/0140-6736(90)93098-a. [DOI] [PubMed] [Google Scholar]
- Seldon P. M., Stevens D. A., Adcock I. M., O'Connor B. J., Barnes P. J., Giembycz M. A. Albuterol does not antagonize the inhibitory effect of dexamethasone on monocyte cytokine release. Am J Respir Crit Care Med. 1998 Mar;157(3 Pt 1):803–809. doi: 10.1164/ajrccm.157.3.9707116. [DOI] [PubMed] [Google Scholar]
- Simons F. E. A comparison of beclomethasone, salmeterol, and placebo in children with asthma. Canadian Beclomethasone Dipropionate-Salmeterol Xinafoate Study Group. N Engl J Med. 1997 Dec 4;337(23):1659–1665. doi: 10.1056/NEJM199712043372304. [DOI] [PubMed] [Google Scholar]
- Simons F. E., Gerstner T. V., Cheang M. S. Tolerance to the bronchoprotective effect of salmeterol in adolescents with exercise-induced asthma using concurrent inhaled glucocorticoid treatment. Pediatrics. 1997 May;99(5):655–659. doi: 10.1542/peds.99.5.655. [DOI] [PubMed] [Google Scholar]
- Stephan W. C., Chick T. W., Avner B. P., Jenne J. W. Tachyphylaxis to inhaled isoproterenol and the effect of methylprednisolone in dogs. J Allergy Clin Immunol. 1980 Feb;65(2):105–109. doi: 10.1016/0091-6749(80)90193-1. [DOI] [PubMed] [Google Scholar]
- Tan K. S., Grove A., McLean A., Gnosspelius Y., Hall I. P., Lipworth B. J. Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients. Am J Respir Crit Care Med. 1997 Jul;156(1):28–35. doi: 10.1164/ajrccm.156.1.9610113. [DOI] [PubMed] [Google Scholar]
- Tan K. S., McFarlane L. C., Lipworth B. J. Concomitant administration of low-dose prednisolone protects against in vivo beta2-adrenoceptor subsensitivity induced by regular formoterol. Chest. 1998 Jan;113(1):34–41. doi: 10.1378/chest.113.1.34. [DOI] [PubMed] [Google Scholar]
- Taylor D. R., Sears M. R., Herbison G. P., Flannery E. M., Print C. G., Lake D. C., Yates D. M., Lucas M. K., Li Q. Regular inhaled beta agonist in asthma: effects on exacerbations and lung function. Thorax. 1993 Feb;48(2):134–138. doi: 10.1136/thx.48.2.134. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Taylor D. R., Town G. I., Herbison G. P., Boothman-Burrell D., Flannery E. M., Hancox B., Harré E., Laubscher K., Linscott V., Ramsay C. M. Asthma control during long-term treatment with regular inhaled salbutamol and salmeterol. Thorax. 1998 Sep;53(9):744–752. doi: 10.1136/thx.53.9.744. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Taylor D. R., Wilkins G. T., Herbison G. P., Flannery E. M. Interaction between corticosteroid and beta-agonist drugs. Biochemical and cardiovascular effects in normal subjects. Chest. 1992 Aug;102(2):519–524. doi: 10.1378/chest.102.2.519. [DOI] [PubMed] [Google Scholar]
- Torphy T. J. Beta-adrenoceptors, cAMP and airway smooth muscle relaxation: challenges to the dogma. Trends Pharmacol Sci. 1994 Oct;15(10):370–374. doi: 10.1016/0165-6147(94)90157-0. [DOI] [PubMed] [Google Scholar]
- Van Metre T. E., Jr Adverse effects of inhalation of excessive amounts of nebulized isoproterenol in status asthmaticus. J Allergy. 1969 Feb;43(2):101–113. doi: 10.1016/0021-8707(69)90130-0. [DOI] [PubMed] [Google Scholar]
- Verberne A. A., Frost C., Roorda R. J., van der Laag H., Kerrebijn K. F. One year treatment with salmeterol compared with beclomethasone in children with asthma. The Dutch Paediatric Asthma Study Group. Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):688–695. doi: 10.1164/ajrccm.156.3.9611067. [DOI] [PubMed] [Google Scholar]
- Waalkens H. J., Gerritsen J., Koëter G. H., Krouwels F. H., van Aalderen W. M., Knol K. Budesonide and terbutaline or terbutaline alone in children with mild asthma: effects on bronchial hyperresponsiveness and diurnal variation in peak flow. Thorax. 1991 Jul;46(7):499–503. doi: 10.1136/thx.46.7.499. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Weersink E. J., Douma R. R., Postma D. S., Koëter G. H. Fluticasone propionate, salmeterol xinafoate, and their combination in the treatment of nocturnal asthma. Am J Respir Crit Care Med. 1997 Apr;155(4):1241–1246. doi: 10.1164/ajrccm.155.4.9105061. [DOI] [PubMed] [Google Scholar]
- Wempe J. B., Postma D. S., Breederveld N., Alting-Hebing D., van der Mark T. W., Koëter G. H. Separate and combined effects of corticosteroids and bronchodilators on airflow obstruction and airway hyperresponsiveness in asthma. J Allergy Clin Immunol. 1992 Mar;89(3):679–687. doi: 10.1016/0091-6749(92)90374-b. [DOI] [PubMed] [Google Scholar]
- Wilding P. J., Clark M. M., Oborne J., Bennett J. A., Tattersfield A. E. Effect of regular terbutaline on the airway response to inhaled budesonide. Thorax. 1996 Oct;51(10):989–992. doi: 10.1136/thx.51.10.989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Woolcock A., Lundback B., Ringdal N., Jacques L. A. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am J Respir Crit Care Med. 1996 May;153(5):1481–1488. doi: 10.1164/ajrccm.153.5.8630590. [DOI] [PubMed] [Google Scholar]
- Yates D. H., Kharitonov S. A., Barnes P. J. An inhaled glucocorticoid does not prevent tolerance to the bronchoprotective effect of a long-acting inhaled beta 2-agonist. Am J Respir Crit Care Med. 1996 Dec;154(6 Pt 1):1603–1607. doi: 10.1164/ajrccm.154.6.8970342. [DOI] [PubMed] [Google Scholar]
- van Essen-Zandvliet E. E., Hughes M. D., Waalkens H. J., Duiverman E. J., Pocock S. J., Kerrebijn K. F. Effects of 22 months of treatment with inhaled corticosteroids and/or beta-2-agonists on lung function, airway responsiveness, and symptoms in children with asthma. The Dutch Chronic Non-specific Lung Disease Study Group. Am Rev Respir Dis. 1992 Sep;146(3):547–554. doi: 10.1164/ajrccm/146.3.547. [DOI] [PubMed] [Google Scholar]
- van Noord J. A., Schreurs A. J., Mol S. J., Mulder P. G. Addition of salmeterol versus doubling the dose of fluticasone propionate in patients with mild to moderate asthma. Thorax. 1999 Mar;54(3):207–212. doi: 10.1136/thx.54.3.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
- van der Molen T., Postma D. S., Turner M. O., Jong B. M., Malo J. L., Chapman K., Grossman R., de Graaff C. S., Riemersma R. A., Sears M. R. Effects of the long acting beta agonist formoterol on asthma control in asthmatic patients using inhaled corticosteroids. The Netherlands and Canadian Formoterol Study Investigators. Thorax. 1997 Jun;52(6):535–539. doi: 10.1136/thx.52.6.535. [DOI] [PMC free article] [PubMed] [Google Scholar]