Figure 7.
Extended activation domain of the dsxRE. The heterotrimeric complex that binds each dsxRE generates a potent splicing activation domain that is composed of contributions from each complex member. The RS domains of 9G8, Tra and the RS1 domain of Tra2 may be involved in mediating spliceosomal recruitment to the regulated splice site. RS2 may be involved in securing complex stability through essential protein–protein interactions.