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CVB3 induces apoptosis in HeLa cells. HeLa cells were infected with CVB3 at a multiplicity of infection of 1, and apoptosis was measured by DAPI staining of nuclei (A), ELISA for the detection of a histone–DNA complex (n = 3 ± SD; ∗, P < 0.05) (B), and Western blot of PARP in cell lysates (C). (Magnification: A, ×120.)
