Dlx gene knockdown perturbs zebrafish pharyngeal tooth morphogenesis. (A) High magnification view of a pharyngeal tooth at 100 hpf in a control injected with the injection solution and no MO. (B) A normal-looking tooth from an identically treated specimen injected with a dlx2b MO. (C) After injection of combined dlx2a and dlx2b MOs, pharyngeal tooth size is reduced (representative example shown). (D) Pharyngeal teeth are even smaller, and are now misshapen, after simultaneous injection with MOs against dlx2a, dlx2b, dlx3b, and dlx5a. (Scale bar: 10 μm.)