Table 1.
Heart rate and mean arterial pressure findings
| Group | Time (hours) | ||||||
| 0 | 0.5 | 1 | 2 | 3 | 4 | ||
| Heart rate (beats/minute) | CON | 335 ± 18 | 347 ± 20 | 351 ± 20 | 349 ± 21 | 343 ± 19 | 339 ± 9*† |
| LPS | 342 ± 11 | 347 ± 12 | 365 ± 17 | 387 ± 11‡ | 378 ± 11‡ | 390 ± 9‡ | |
| DPX | 321 ± 9 | 366 ± 9 | 399 ± 7§ | 394 ± 8§ | 384 ± 15§ | 394 ± 12§ | |
| Mean arterial pressure (mmHg) | CON | 120 ± 5 | 119 ± 8*† | 109 ± 7* | 107 ± 8 | 116 ± 3 | 118 ± 5* |
| LPS | 116 ± 3 | 74 ± 2‡ | 87 ± 3‡ | 94 ± 4‡ | 88 ± 3‡ | 89 ± 5‡ | |
| DPX | 120 ± 6 | 70 ± 2§ | 107 ± 7§ | 102 ± 7§ | 104 ± 8§ | 99 ± 9§ | |
CON, control group; DPX, DPX group (endotoxin plus dopexamine); LPS, LPS group (endotoxin infusion only). *P < 0.05 CON versus LPS; †P < 0.05 CON versus DPX; ‡P < 0.05 LPS versus LPS at baseline; §P < 0.05 DPX versus DPX at baseline.