Table 1.
Standard medical therapy (n = 6) | Molecular adsorbent recirculating system + standard medical therapy (n = 6) | Prometheus + standard medical therapy (n = 6) | P value | |
Age (years) | 55.8 ± 1.9 | 54.5 ± 3.0 | 43.2 ± 4.7 | 0.097 |
Sex (male/female) | 3/3 | 5/1 | 4/2 | 0.585 |
Serum bilirubin (mg%) | 29.9 ± 4.5 | 25.6 ± 3.6 | 34.3 ± 1.9 | 0.245 |
Prothrombin time | 37.6 ± 2.9 | 39.8 ± 4.0 | 40.9 ± 7.0 | 0.888 |
Albumin (g/l) | 26.3 ± 1.7 | 27.8 ± 0.8 | 29.4 ± 1.7 | 0.348 |
Creatinin (mg%) | 1.5 ± 0.3 | 1.6 ± 0.5 | 1.5 ± 0.2 | 0.984 |
Hepatic encephalopathy score | 1 ± 0.4 | 1.5 ± 0.2 | 1.2 ± 0.4 | 0.473 |
Hepatic venous pressure gradient (mmHg) | 16.8 ± 1.4 | 19.2 ± 1.0 | 15.5 ± 2.5 | 0.245 |
Child-Pugh score | 13 ± 0.4 | 12.7 ± 0.3 | 11.8 ± 0.3 | 0.070 |
Sequential Organ Failure Assessment score | 9.3 ± 0.9 | 8.3 ± 0.8 | 9.2 ± 0.7 | 0.637 |
Model for End-stage Liver Disease score | 24.3 ± 2.4 | 22.7 ± 2.2 | 29.7 ± 1.7 | 0.081 |
Maddrey's discriminant function | 70.5 ± 10.5 | 55.6 ± 7.3 | 63.2 ± 18.1 | 0.501 |
Data presented as the mean ± standard error of the mean, and represent values of the day before start of study.