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Several extended biopsy templates have been proposed over the past years. All attempt to incorporate increased core number and sampling of the far-lateral region of the peripheral zone. (A) The 13-core, “5-region” biopsy12,13 incorporates 4 far-lateral cores. (B) The 11-core, multisite-directed biopsy14 includes several midsagittal cores. (C) The current 12-core biopsy used at New York University incorporates a far-lateral sextant sampling.
