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. 2005 Aug 1;146(4):487–497. doi: 10.1038/sj.bjp.0706363

Figure 2.

Figure 2

Effects of chronic in vivo administration of nitroglycerine (NTG) on ACh-induced membrane potential changes in AVECs. (a) Effects of 0.03 μM ACh on membrane potential in an AVEC from an NTG-untreated control rabbit (‘Control rabbit') or an NTG-treated rabbit (‘NTG-treated rabbit'). The RMP was −51.4 mV in Control rabbit and this being −51.5 mV in NTG-treated rabbit. (b) Effects of 0.3 μM ACh (as in a). The RMP was −51.2 mV in Control rabbit and this being −51.3 mV in NTG-treated rabbit. (c) Effects of 3 μM ACh (as in a). The RMP was −51.3 mV in Control rabbit and this being −51.4 mV in NTG-treated rabbit. The concentration-dependent effects of ACh shown in (a)–(c) were obtained from a single endothelial cell in each type of rabbit.