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. 2005 Aug 1;146(4):585–595. doi: 10.1038/sj.bjp.0706342

Figure 5.

Figure 5

Inactivation properties of the XE991-sensitive current. (a) Inactivation of the XE991-sensitive current was investigated by a two-pulse protocol described in the inset. Currents were evoked every 60 s. Examples of currents evoked by this protocol in the absence (ai) and presence (aii) of 30 μM XE991. XE991-sensitive recordings from the same cell as (a) are shown in panel (bi). An enlargement of the XE991-sensitive currents at VT (0 mV) is shown in (bii). Panel c shows the mean data from experiments typified in (a). Vertical axis is the mean amplitude of the XE991-sensitive current at VT normalised to the maximum current at VT. Horizontal axis is the prepotential (mV). Data points were fitted with a Boltzmann function to give V1/2 inact=−54.3±2.1 mV (n=4). Activation data were normalised peak amplitudes at various prepotentials. Data were fitted with a Boltzmann function to give V1/2=7.1±2.7 mV (n=4).