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Body weight, renal response to the water load and urinary excretion of sodium in baseline conditions in cirrhotic rats prior to chronic treatment with RWJ-351647 or vehicle
| RWJ-351647 (n=6) | Vehicle (n=6) | |
|---|---|---|
| Body wt (g) | 510±23 | 540±17 |
| % Water load excreted | 38±8 | 32±6 |
| mUOsm (mOsm kg−1) | 254±70 | 233±27 |
| UNaV (μEq min−1) | 0.26±0.14 | 0.49±0.1 |
