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. 2005 Sep 5;146(6):826–833. doi: 10.1038/sj.bjp.0706385

Figure 1.

Figure 1

Separation of a voltage-gated K+ current into inactivating A (KA) and delayed-rectifier (KDR) components in dorsal horn neurons. (a) All K+ current (KA+KDR) was activated by a voltage step to +20 mV after a 150-ms prepulse to −120 mV (left). The delayed-rectifier component of the K+ current (KDR) was activated by a voltage step to +20 mV after a 150-ms prepulse to −60 mV (middle). Inactivating A current was obtained by digital subtraction of delayed-rectifier current from total current: KA=K+−KDR. (b) Offline subtraction of leak and transient currents for calculation of KDR by hyperpolarizing impulses to −120 mV. Dotted lines indicate zero level.