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. 2005 Sep 5;146(6):826–833. doi: 10.1038/sj.bjp.0706385

Figure 4.

Figure 4

Effect of ketamine on KA currents in somata. (a) KA current in control solution and in the presence of 1 mM S(+)- and R(−)-ketamine. The currents were activated by a 250 ms voltage step to +40 mV following a 150 ms prepulse to –120 mV. Holding potential was –80 mV. The procedure of separating KA currents from other K+ currents is explained in the Methods section. (b) Summarized data showing relative KA current after application of ketamine (white bars), or R(−)-enantiomer (grey bars), or S(+)-enantiomer (black bars), elicited by the test potential at +40 mV. Values are mean±s.e.m. (n=7).