. 2005 Sep 5;146(6):826–833. doi: 10.1038/sj.bjp.0706385

Table 1.

IC₅₀ values for ketamine and both enantiomers S(+)- and R(−)-ketamine

	Racemate		S(+)-ketamine		R(−)-ketamine		Stereopotency ratio R(−)/S(+)
	IC₅₀ (μM)	Hill	IC₅₀ (μM)	Hill	IC₅₀ (μM)	Hill
Na⁺ current	199±8	0.74	128±3	1.08	269±9^*	0.99	2.10
K_DR current (peak)	424±9	0.72	323±2	0.79	363±19	0.72	1.12
K_DR current (tail)	338±9	0.78	266±7	0.72	196±33	0.74	0.73

Number of neurons in the parentheses.

P<0.05 for difference from S(+)-ketamine.