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Emax and pD2 values for IRL1620-induced contraction of endothelium-denuded (Endo−) and endothelium-intact (Endo+) rat carotid in the absence or presence of BQ123 and BQ788
| Groups | Emax (g) | pD2 | n |
|---|---|---|---|
| Endo+ | 0.040±0.009 | 7.27±0.26 | 7 |
| Endo− | 0.067±0.008* | 8.03±0.21 | 6 |
| Endo+ plus BQ123 (3 μM) | 0.041±0.009 | 7.43±0.21 | 5 |
| Endo+ plus BQ788 (3 μM) | — | — | 5 |
Values are means±s.e.m. of n preparations.
P<0.05 vs Endo+ (ANOVA).
